Using fMRI to Study Cognitive Fatigue in MS (with Zeposia®)

Study investigates the effect of disease-modifying medications, specifically Zeposia®, on cognitive fatigue in multiple sclerosis. Cognitive fatigue is the kind of fatigue that occurs after intense mental concentration, such as after a session of problem-solving.

Actively Recruiting
Yes
Duration

Session 1: Functional magnetic resonance imaging (fMRI) session (75 minutes) followed by paper and pencil tests (3 hours). Session can be split into two separate visits.

Session 2: 6-month follow-up fMRI session (75 minutes) followed by paper and pencil tests (3 hours).

Session 3: 12-month follow-up fMRI session (75 minutes) followed by paper and pencil tests (3 hours).

Inclusion Criteria

• Individuals diagnosed with relapsing remitting multiple sclerosis (RRMS) who have been prescribed Zeposia by their medical doctor
• 18-64 years of age
• Speak and read English fluently
Or
• Healthy volunteers 
• 18-64 years of age
• Speak and read English fluently.

Compensation

$100 per session for a total of $300 upon completion 

IRB Number:

R-1150-21